Solve the insoluble with AFFINISOL™ HPMC HME

Finding a solution for poorly soluble drug compounds is the leading challenge faced by the pharmaceutical industry. AFFINISOL™ hydroxypropyl methylcellulose (HPMC) is a water-soluble cellulosic polymer from Pharma Solutions, designed to enhance the solubility of drugs and unlock their full therapeutic potential.

Our AFFINISOL™ HPMC HME polymers are uniquely tailored to address solubility by maintaining stable solid dispersions and inhibiting the recrystallization of APIs in formulation via hot melt extrusion (HME) or spray-drying (SD). Through these actions, AFFINISOL™ HPMC HME helps to simplify formulation requirements, improve physical stability and boost versatility in drug release profiles; improving the solubility and bioavailability for both immediate release and controlled release applications.

Product benefits
  • Solubility enhancer
  • Stabilizing polymer
  • Versatile thermal processability
  • Soluble in organic solvent
  • Expands functionality of immediate release and controlled release drugs
Key applications
  • Solubility enhancement
  • Hot melt extrusion and melt granulation
  • Spray-drying
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Ready to start your AFFINISOL™ collaboration? Speak to one of our experts today.

We can help you along your product development process. Contact us to start your journey to success.

Contact Us

We can help you along your product development process. Contact us to start your journey to success.